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Through a number of mechanisms of action connected to the homeostatic preservation of the hypothalamicpituitary-adrenal (HPA) axis and the regulation of important mediators of the stress response, ashwagandha is regarded as an adaptogen that aids in the restoration of homeostasis by counteracting external stimuli as nonspecific regulators [158]

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Folia microbiologica 61, 399403

In the following sections, we delineate the mechanisms and regulatory dimensions governing these astrocytic state transitions and their contributions to reactive diversity under environmental stressors and pathological challenges